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The two extremes of this range are the pro-inflammatory M1 phenotype, associated with active microbial killing, and the M2 phenotype, associated with immune suppression, tissue remodeling and angiogenesis [231]

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Dec 8: In an historic moment Friday, the FDA approved the first-ever gene therapy based on the Nobel Prize-winning CRISPR/Cas9 gene editing system discovered more than a decade ago by Jennifer Doudna and Emmanuelle Charpentier